Search | VHL Search Portal

1.

Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability.

Murphy, Ryan J; Gunasingh, Gency; Haass, Nikolas K; Simpson, Matthew J.

PLoS Comput Biol ; 19(1): e1010833, 2023 01.

Article in English | MEDLINE | ID: mdl-36634128

2.

H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase.

Ravindran Menon, Dinoop; Hammerlindl, Heinz; Gimenez, Gregory; Hammerlindl, Sabrina; Zuegner, Elmar; Torrano, Joachim; Bordag, Natalie; Emran, Abdullah Al; Giam, Maybelline; Denil, Simon; Pavelka, Norman; Tan, Aik-Choon; Sturm, Richard A; Haass, Nikolas K; Rancati, Giulia; Herlyn, Meenhard; Magnes, Christoph; Eccles, Michael R; Fujita, Mayumi; Schaider, Helmut.

Drug Resist Updat ; 71: 100993, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37639774

3.

Rapid initiation of cell cycle reentry processes protects neurons from amyloid-ß toxicity.

Ippati, Stefania; Deng, Yuanyuan; van der Hoven, Julia; Heu, Celine; van Hummel, Annika; Chua, Sook Wern; Paric, Esmeralda; Chan, Gabriella; Feiten, Astrid; Fath, Thomas; Ke, Yazi D; Haass, Nikolas K; Ittner, Lars M.

Proc Natl Acad Sci U S A ; 118(12)2021 03 23.

Article in English | MEDLINE | ID: mdl-33737393

4.

Head and neck cancer patient-derived tumouroid cultures: opportunities and challenges.

Basnayake, B W M Thilini J; Leo, Paul; Rao, Sudha; Vasani, Sarju; Kenny, Lizbeth; Haass, Nikolas K; Punyadeera, Chamindie.

Br J Cancer ; 128(10): 1807-1818, 2023 05.

Article in English | MEDLINE | ID: mdl-36765173

5.

The MC1R r allele does not increase melanoma risk in MITF E318K carriers.

Wallingford, Courtney K; Demeshko, Anastassia; Krishnakripa, Asha Krishnankutty; Smit, Darren J; Duffy, David L; Betz-Stablein, Brigid; Pflugfelder, Annette; Jagirdar, Kasturee; Holland, Elizabeth; Mann, Graham J; Primiero, Clare A; Yanes, Tatiane; Malvehy, Josep; Badenas, Cèlia; Carrera, Cristina; Aguilera, Paula; Olsen, Catherine M; Ward, Sarah V; Haass, Nikolas K; Sturm, Richard A; Puig, Susana; Whiteman, David C; Law, Matthew H; Cust, Anne E; Potrony, Miriam; Soyer, H Peter; McInerney-Leo, Aideen M.

Br J Dermatol ; 188(6): 770-776, 2023 05 24.

Article in English | MEDLINE | ID: mdl-36879448

6.

Formation and Growth of Co-Culture Tumour Spheroids: New Compartment-Based Mathematical Models and Experiments.

Murphy, Ryan J; Gunasingh, Gency; Haass, Nikolas K; Simpson, Matthew J.

Bull Math Biol ; 86(1): 8, 2023 12 13.

Article in English | MEDLINE | ID: mdl-38091169

7.

Synchronized oscillations in growing cell populations are explained by demographic noise.

Gavagnin, Enrico; Vittadello, Sean T; Gunasingh, Gency; Haass, Nikolas K; Simpson, Matthew J; Rogers, Tim; Yates, Christian A.

Biophys J ; 120(8): 1314-1322, 2021 04 20.

Article in English | MEDLINE | ID: mdl-33617836

8.

Mathematical Model of Tumour Spheroid Experiments with Real-Time Cell Cycle Imaging.

Jin, Wang; Spoerri, Loredana; Haass, Nikolas K; Simpson, Matthew J.

Bull Math Biol ; 83(5): 44, 2021 03 20.

Article in English | MEDLINE | ID: mdl-33743088

9.

A novel mathematical model of heterogeneous cell proliferation.

Vittadello, Sean T; McCue, Scott W; Gunasingh, Gency; Haass, Nikolas K; Simpson, Matthew J.

J Math Biol ; 82(5): 34, 2021 03 12.

Article in English | MEDLINE | ID: mdl-33712945

10.

Examining Go-or-Grow Using Fluorescent Cell-Cycle Indicators and Cell-Cycle-Inhibiting Drugs.

Vittadello, Sean T; McCue, Scott W; Gunasingh, Gency; Haass, Nikolas K; Simpson, Matthew J.

Biophys J ; 118(6): 1243-1247, 2020 03 24.

Article in English | MEDLINE | ID: mdl-32087771

11.

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models.

Stehbens, Samantha J; Ju, Robert J; Adams, Mark N; Perry, Samuel R; Haass, Nikolas K; Bryant, David M; Pollock, Pamela M.

J Cell Sci ; 131(15)2018 08 10.

Article in English | MEDLINE | ID: mdl-30002137

12.

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.

Guo, Dajiang; Lui, Goldie Y L; Lai, Siew Li; Wilmott, James S; Tikoo, Shweta; Jackett, Louise A; Quek, Camelia; Brown, Darren L; Sharp, Danae M; Kwan, Rain Y Q; Chacon, Diego; Wong, Jason H; Beck, Dominik; van Geldermalsen, Michelle; Holst, Jeff; Thompson, John F; Mann, Graham J; Scolyer, Richard A; Stow, Jennifer L; Weninger, Wolfgang; Haass, Nikolas K; Beaumont, Kimberley A.

Int J Cancer ; 144(12): 3070-3085, 2019 06 15.

Article in English | MEDLINE | ID: mdl-30556600

13.

Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics.

Vittadello, Sean T; McCue, Scott W; Gunasingh, Gency; Haass, Nikolas K; Simpson, Matthew J.

Biophys J ; 114(5): 1241-1253, 2018 03 13.

Article in English | MEDLINE | ID: mdl-29539409

14.

HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma.

Gallagher, Stuart J; Gunatilake, Dilini; Beaumont, Kimberley A; Sharp, Danae M; Tiffen, Jessamy C; Heinemann, Anja; Weninger, Wolfgang; Haass, Nikolas K; Wilmott, James S; Madore, Jason; Ferguson, Peter M; Rizos, Helen; Hersey, Peter.

Int J Cancer ; 142(9): 1926-1937, 2018 05 01.

Article in English | MEDLINE | ID: mdl-29210065

15.

Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities.

Haass, Nikolas K; Gabrielli, Brian.

Exp Dermatol ; 26(7): 649-655, 2017 07.

Article in English | MEDLINE | ID: mdl-28109167

16.

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

Ke, Yazi D; van Hummel, Annika; Stevens, Claire H; Gladbach, Amadeus; Ippati, Stefania; Bi, Mian; Lee, Wei S; Krüger, Sarah; van der Hoven, Julia; Volkerling, Alexander; Bongers, Andre; Halliday, Glenda; Haass, Nikolas K; Kiernan, Matthew; Delerue, Fabien; Ittner, Lars M.

Acta Neuropathol ; 130(5): 661-78, 2015 Nov.

Article in English | MEDLINE | ID: mdl-26437864

17.

Targeting glutamine transport to suppress melanoma cell growth.

Wang, Qian; Beaumont, Kimberley A; Otte, Nicholas J; Font, Josep; Bailey, Charles G; van Geldermalsen, Michelle; Sharp, Danae M; Tiffen, Jessamy C; Ryan, Renae M; Jormakka, Mika; Haass, Nikolas K; Rasko, John E J; Holst, Jeff.

Int J Cancer ; 135(5): 1060-71, 2014 Sep 01.

Article in English | MEDLINE | ID: mdl-24531984

18.

Melanoma never says die.

Haass, Nikolas K; Schumacher, Udo.

Exp Dermatol ; 23(7): 471-2, 2014 Jul.

Article in English | MEDLINE | ID: mdl-24684560

19.

VEGF/VEGFR axis and its signaling in melanoma: Current knowledge toward therapeutic targeting agents and future perspectives.

Malekan, Mohammad; Haass, Nikolas K; Rokni, Ghasem Rahmatpour; Gholizadeh, Nasim; Ebrahimzadeh, Mohammad Ali; Kazeminejad, Armaghan.

Life Sci ; 345: 122563, 2024 May 15.

Article in English | MEDLINE | ID: mdl-38508233

20.

Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical Modeling.

Spoerri, Loredana; Beaumont, Kimberley A; Anfosso, Andrea; Murphy, Ryan J; Browning, Alexander P; Gunasingh, Gency; Haass, Nikolas K.

Methods Mol Biol ; 2764: 291-310, 2024.

Article in English | MEDLINE | ID: mdl-38393602

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export:

Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability.

H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase.

Rapid initiation of cell cycle reentry processes protects neurons from amyloid-ß toxicity.

Head and neck cancer patient-derived tumouroid cultures: opportunities and challenges.

The MC1R r allele does not increase melanoma risk in MITF E318K carriers.

Formation and Growth of Co-Culture Tumour Spheroids: New Compartment-Based Mathematical Models and Experiments.

Synchronized oscillations in growing cell populations are explained by demographic noise.

Mathematical Model of Tumour Spheroid Experiments with Real-Time Cell Cycle Imaging.

A novel mathematical model of heterogeneous cell proliferation.

Examining Go-or-Grow Using Fluorescent Cell-Cycle Indicators and Cell-Cycle-Inhibiting Drugs.

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models.

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.

Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics.

HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma.

Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities.

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

Targeting glutamine transport to suppress melanoma cell growth.

Melanoma never says die.

VEGF/VEGFR axis and its signaling in melanoma: Current knowledge toward therapeutic targeting agents and future perspectives.

Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical Modeling.